Cicatricial (scarring) alopecia results from irreversible damage to epithelial stem cells located in the bulge region of the hair follicle, generally as a result of inflammatory mechanisms (eg, in the context of autoimmune disease).
Is scarring alopecia an autoimmune disease?
Like scarring alopecia, alopecia areata is somewhat miscategorized because, unlike traditional baldness as we know it, it is actually an autoimmune disease symptom. Essentially, the immune system attacks the follicles, eventually causing them to stop growing. Some scarring alopecia can be caused by autoimmune diseases.
Which type of alopecia is an autoimmune disease?
What causes alopecia areata? Alopecia areata is an autoimmune disease. This means that your immune system mistakenly attacks a part of your body. When you have alopecia areata, cells in your immune system surround and attack your hair follicles (the part of your body that makes hair).
What are three types of alopecia that are caused by an autoimmune disorder?
Three of the more well-known types of alopecia areata
- Alopecia areata patchy — The most common form, with one or more coin-sized hairless patches on the scalp or other areas of the body.
- Alopecia totalis — Total loss of the hair on the scalp.
- Alopecia universalis — Complete loss of hair on the scalp, face and body.
What causes Cicatricial alopecia?
Cicatricial alopecia is primarily caused by inflammation that damages the hair follicle, although the damage may also be caused by a trauma such as a burn or serious infection. The inflammation could involve different types of cells, including lymphocytes, natural killer cells, or a combination of cell types.
What does Cicatricial mean?
pl. cic·a·tri·ces (sĭk′ə-trī′sēz, sĭ-kā′trĭ-sēz′) A scar left by the formation of new connective tissue over a healing sore or wound.
Is Cicatricial alopecia contagious?
If the stem cells and sebaceous gland are destroyed, there is no possibility for regeneration of the hair follicle, leading to permanent hair loss. Cicatricial alopecias are not contagious.
Can alopecia lead to other autoimmune diseases?
Studies show that people with alopecia areata can have other autoimmune diseases, such as thyroid disease. However, the fact that you have alopecia areata doesn’t mean you will automatically develop another autoimmune disease.
How do you stop autoimmune hair loss?
As alopecia areata is an autoimmune disease, several treatments involve the use of immunosuppressant drugs. Other forms of treatment involve stimulating hair growth. This works best for those with less severe hair loss.
Is alopecia a disability?
Alopecia areata is not medically disabling; persons with alopecia areata are usually in excellent health. But emotionally, this disease can be challenging, especially for those with extensive hair loss.
Is Alopecia a lifelong disease?
Alopecia areata occurs when the body’s immune system mistakes hair follicles as foreign and attacks them. This causes the hairs to fall out. This specific form of autoimmunity is a lifelong tendency that can be inherited from either parent.
What medical conditions cause alopecia?
Medical conditions that can cause hair loss include: thyroid disease. alopecia areata (an autoimmune disease that attacks hair follicles) scalp infections like ringworm.
Hair loss can also be due to medications used to treat:
- high blood pressure.
- heart problems.
Can an autoimmune disease cause hair loss?
Some autoimmune disorders can be particularly associated with hair loss such as, alopecia, lupus, Hashimoto’s, psoriasis, and Crohn’s Disease/ulcerative colitis. Some medications to treat the autoimmune disease can lead to hair loss.
Is CCCA an autoimmune disease?
Factors that could be contributory to the development of CCCA are genetics, history of autoimmune disease, and various hairstyling practices such as excessive heat and tension chemical relaxers on the scalp that are known to be used in the black community.
How can Cicatricial alopecia be prevented?
The medical treatment of cicatricial alopecia.
What is centrifugal Cicatricial alopecia?
Central centrifugal cicatricial alopecia (CCCA) is a disease characterized by permanent hair loss in the crown region of the scalp, inflammation, and scarring. It occurs almost exclusively in black women aged 30 to 55 years.